During the first week of August, I attended a conference hosted by Aniridia Foundation International (AFI). Aniridia means “lack of the iris,” which is the colored ring around the pupil of the eye. Advances in research and development have shown that the impact of aniridia extends beyond the eye and can affect the development and maintenance of the eyes, pancreas, central nervous system, olfactory system, and parts of the brain. Aniridia is caused by a mutation of the PAX 6 gene which is now known to control development of the eyes as well as several systems in the body.